4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-
Modify Date: 2025-08-25 14:41:13
4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo- structure
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Common Name | 4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo- | ||
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| CAS Number | 27430-18-8 | Molecular Weight | 222.22 | |
| Density | 1.54g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H6N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin (HY-16560). CD00509 has anti-tumor activity[1]. |
| Name | 5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione |
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| Synonym | More Synonyms |
| Description | CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin (HY-16560). CD00509 has anti-tumor activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.54g/cm3 |
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| Molecular Formula | C9H6N2O3S |
| Molecular Weight | 222.22 |
| Exact Mass | 222.01000 |
| PSA | 103.43000 |
| LogP | 0.85150 |
| Index of Refraction | 1.685 |
| HS Code | 2934999090 |
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~92%
4,6(1H,5H)-Pyri... CAS#:27430-18-8 |
| Literature: Paasz, Aleksandra Synthesis, 2010 , # 23 art. no. T12110SS, p. 4021 - 4032 |
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~%
4,6(1H,5H)-Pyri... CAS#:27430-18-8 |
| Literature: Dox; Plaisance Journal of the American Chemical Society, 1916 , vol. 38, p. 2165 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 5-(2-furylmethylene)-2-thioxo-1,3-dihydropyrimidine-4,6-dione |
| 5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione |
| 5-furan-2-ylmethylene-2-thioxodihydropyrimidine-4,6-dione |
| 5-furfurylidene-2-thio-barbituric acid |
| 5-Furfuryliden-2-thio-barbitursaeure |
| 5-furfurylidene-2-thioxo-dihydro-pyrimidine-4,6-dione |
| 5-(furan-2'-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione |