DNA-PK-IN-5
Modify Date: 2025-08-31 12:25:40
DNA-PK-IN-5 structure
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Common Name | DNA-PK-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 2719736-43-1 | Molecular Weight | 418.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H22N8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DNA-PK-IN-5DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-5 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021204111A1, compound 2)[1]. |
| Name | DNA-PK-IN-5 |
|---|
| Description | DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-5 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021204111A1, compound 2)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C21H22N8O2 |
|---|---|
| Molecular Weight | 418.45 |
| InChIKey | BIXRNGNRPTYYQW-UHFFFAOYSA-N |
| SMILES | Cc1cc2nccnc2cc1Nc1ncc2c(n1)n(N1CC3CCC(C1)O3)c(=O)n2C |