Oxametacin

Modify Date: 2025-09-05 19:57:00

Oxametacin structure	Common Name	Oxametacin
	CAS Number	27035-30-9	Molecular Weight	372.80200
	Density	1.35g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₇ClN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Oxametacin

Oxametacin is a anti-inflammatory compound used with care in anticoagulated patients. It has analgesic, antipyretic and anti-inflammatory properties comparable to those of indomethacin.

Name	oxametacin
Synonym	More Synonyms

Density	1.35g/cm3
Molecular Formula	C₁₉H₁₇ClN₂O₄
Molecular Weight	372.80200
Exact Mass	372.08800
PSA	80.56000
LogP	3.73900
Index of Refraction	1.63

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL3668500

CHEMICAL NAME :: Indole-3-acetohydroxamic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-

CAS REGISTRY NUMBER :: 27035-30-9

BEILSTEIN REFERENCE NO. :: 0497721

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H17-Cl-N2-O4

MOLECULAR WEIGHT :: 372.83

WISWESSER LINE NOTATION :: T56 BNJ BVR DG& C1 D1VMQ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

HS Code	2933990090

1-(4-Chlorobenz...

CAS#:20357-37-3

Oxametacin

CAS#:27035-30-9

Literature: Wey, Shiow-Jyi; Augustyniak, Michael E.; Cochran, Edward D.; Ellis, James L.; Fang, Xinqin; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Melim, Terry L.; Murty, Madhavi G.; Richardson, Steward K.; Schroeder, Joseph D.; Selig, William M.; Trocha, A. Mark; Wexler, Roseanne S.; Young, Delano V.; Zemtseva, Irina S.; Zifcak, Brian M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 25 p. 6367 - 6382

Indometacin

CAS#:53-86-1

Oxametacin

CAS#:27035-30-9

Literature: Flynn; Capiris; Cetenko; Connor; Dyer; Kostlan; Nies; Schrier; Sircar Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2070 - 2072

Precursor 2
CAS#:20357-37-3 1-(4-Chlorobenz... CAS#:53-86-1 Indometacin
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Oxametacinum [INN-Latin]

Oxametacine [INN-French]

Oxametacin

2-[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide

Oxametacin [INN]

Acido indoxamico [Italian]

Indoxamic acid

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-hydroxyacetamide

Oxametacine

2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethanehydroxamic acid

Oxametacina [INN-Spanish]

1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetohydroxamic acid

Oxamethacin

1-(p-chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetohydroxamic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Oxametacin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Oxametacin
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: oxametacin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Oxametacin

Use of Oxametacin

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Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synthetic Route

Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.