ATX inhibitor 21

Modify Date: 2025-09-14 17:08:22

Use of ATX inhibitor 21

ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].

Name	ATX inhibitor 21

Description	ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	Autotaxin:3490 ± 170 nM (IC50)
References	[1]. Jia F, et al. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorg Med Chem. 2020 Nov 15;28(22):115795.

Molecular Formula	C₂₆H₂₅F₂N₅O₂S
Molecular Weight	509.57