DPP

Modify Date: 2024-01-03 17:56:08

DPP structure	Common Name	DPP
	CAS Number	2668267-47-6	Molecular Weight	926.70
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₄₀Cl₂N₂O₁₀Pt	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DPP

DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].

Name	DPP

Description	DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> JAK/STAT Signaling >> STAT
References	[1]. Cai L, et al. Platinum(IV) Complexes as Inhibitors of STAT3 and Regulators of the Tumor Microenvironment To Control Breast Cancer. J Med Chem. 2023 Aug 24;66(16):11351-11364.

Molecular Formula	C₃₆H₄₀Cl₂N₂O₁₀Pt
Molecular Weight	926.70

DPP

Use of DPP

Names

DPP Biological Activity

Chemical & Physical Properties