SSR 146977
Modify Date: 2025-08-25 12:01:59
SSR 146977 structure
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Common Name | SSR 146977 | ||
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| CAS Number | 264618-44-2 | Molecular Weight | 621.64 | |
| Density | 1.26 | Boiling Point | N/A | |
| Molecular Formula | C35H42Cl2N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SSR 146977SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM[1]. |
| Name | N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-piperidinyl]-N,N-dimethylureahydrochloride |
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| Description | SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM[1]. |
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| Related Catalog | |
| Target |
NK3 |
| References |
| Density | 1.26 |
|---|---|
| Molecular Formula | C35H42Cl2N4O2 |
| Molecular Weight | 621.64 |
| InChIKey | XWPBINGFFFZAOZ-UMSFTDKQSA-N |
| SMILES | CN(C)C(=O)NC1(c2ccccc2)CCN(CCCC2(c3ccc(Cl)c(Cl)c3)CCCN(C(=O)c3ccccc3)C2)CC1 |
| Storage condition | Store at +4°C |