Tavilermide
Modify Date: 2024-01-03 12:10:39
Tavilermide structure
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Common Name | Tavilermide | ||
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| CAS Number | 263251-78-1 | Molecular Weight | 580.54400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H32N6O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TavilermideTavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic. |
| Name | 3-[(5S,8S,11S)-8-(4-aminobutyl)-5-(carboxymethylcarbamoyl)-16-nitro-7,10,13-trioxo-2-oxa-6,9,12-triazabicyclo[12.4.0]octadeca-1(14),15,17-trien-11-yl]propanoic acid |
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| Synonym | More Synonyms |
| Description | Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic. |
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| Related Catalog | |
| Target |
TrkA[1] |
| In Vitro | Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye.Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF[1]. |
| References |
| Molecular Formula | C24H32N6O11 |
|---|---|
| Molecular Weight | 580.54400 |
| Exact Mass | 580.21300 |
| PSA | 286.03000 |
| LogP | 1.26590 |
| Storage condition | 2-8℃ |
| d-3 |
| unii-nmg938vj6t |
| Tavilermide |