Certepetide

Modify Date: 2025-09-26 12:43:39

Certepetide structure	Common Name	Certepetide
	CAS Number	2580154-02-3	Molecular Weight	989.09
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₇H₆₀N₁₄O₁₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Certepetide

Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary drug conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors[1][2][3].

Name	Certepetide

Description	Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary drug conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Complement System Signaling Pathways >> Cytoskeleton >> Integrin
Target	Alphav-integrins, NRP-1[3].
References	[1]. https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/pl127.pdf?sfvrsn=8544ca1e_3&download=true [2]. Ruoslahti Erkki, et al. Methods for treating pancreatic cancer and other solid tumors. WO2021226148. [3]. Andrew Peter Dean, et al. Updated single institution outcome data from the first-in-human CEND-1 trial in metastatic pancreatic cancer. Journal of Clinical Oncology 2021 39:15_suppl, e16274-e16274

Molecular Formula	C₃₇H₆₀N₁₄O₁₄S₂
Molecular Weight	989.09

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Certepetide
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Purity: 99.0%
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Use of Certepetide

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Certepetide Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.