EGFR-IN-82
Modify Date: 2024-01-12 08:05:19
EGFR-IN-82 structure
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Common Name | EGFR-IN-82 | ||
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| CAS Number | 2568086-81-5 | Molecular Weight | 694.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H41BrN9O2P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR-IN-82EGFR-IN-82 (Cmpound 8a) is a potent and orally active EGFR inhibitor with IC50 values of 0.09 and 0.06 nM for EGFRL858R/T790M/C797S and EGFRDel19/T790M/C797S, respectively. EGFR-IN-82 has no significant effect on EGFRWT. EGFR-IN-82 has anti-proliferative activity and inhibits tumor formation in nude mice. EGFR-IN-82 can be used in non-small cell lung cancer research [1]. |
| Name | EGFR-IN-82 |
|---|
| Description | EGFR-IN-82 (Cmpound 8a) is a potent and orally active EGFR inhibitor with IC50 values of 0.09 and 0.06 nM for EGFRL858R/T790M/C797S and EGFRDel19/T790M/C797S, respectively. EGFR-IN-82 has no significant effect on EGFRWT. EGFR-IN-82 has anti-proliferative activity and inhibits tumor formation in nude mice. EGFR-IN-82 can be used in non-small cell lung cancer research [1]. |
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| Related Catalog | |
| Target |
0.09 , 0.06 nM (EGFRL858R/T790M/C797S, EGFRDel19/T790M/C797S) |
| References |
| Molecular Formula | C32H41BrN9O2P |
|---|---|
| Molecular Weight | 694.60 |