HIV-1 inhibitor-22

Modify Date: 2024-04-03 17:25:20

HIV-1 inhibitor-22 structure	Common Name	HIV-1 inhibitor-22
	CAS Number	2554618-33-4	Molecular Weight	550.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₆N₆O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIV-1 inhibitor-22

HIV-1 inhibitor-22 (compound 11a) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 3.63 μM for HIV-1 RT. HIV-1 inhibitor-22 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 0.304 μM and 0.201 μM, also has low cytotoxicity (CC50 > 227 μM)[1]

Name	HIV-1 inhibitor-22

Description	HIV-1 inhibitor-22 (compound 11a) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 3.63 μM for HIV-1 RT. HIV-1 inhibitor-22 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 0.304 μM and 0.201 μM, also has low cytotoxicity (CC50 > 227 μM)[1]
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1 (WT):0.304 μM (EC50) HIV-1 (K103N):0.201 μM (EC50)
References	[1]. Han S, et al. Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem. 2020;185:111874.

Molecular Formula	C₃₀H₂₆N₆O₃S
Molecular Weight	550.63

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HIV-1 inhibitor-22

Use of HIV-1 inhibitor-22

Names

HIV-1 inhibitor-22 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.