PROTAC BRD4 Degrader-21

Modify Date: 2024-01-17 11:58:05

PROTAC BRD4 Degrader-21 Structure
PROTAC BRD4 Degrader-21 structure
Common Name PROTAC BRD4 Degrader-21
CAS Number 2503036-46-0 Molecular Weight 925.97
Density N/A Boiling Point N/A
Molecular Formula C47H54Cl2N10O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BRD4 Degrader-21


PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].

 Names

Name PROTAC BRD4 Degrader-21

 PROTAC BRD4 Degrader-21 Biological Activity

Description PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].
Related Catalog
References

[1]. Weiwen Ying, et.al. Methods and compositions for targeted protein degradation

 Chemical & Physical Properties

Molecular Formula C47H54Cl2N10O4S
Molecular Weight 925.97
InChIKey BKCLODCLAKHBOU-KYYDUREMSA-N
SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)N1CCC(CN3CCN(Cc4ccc(-n5c(-c6cc(C(C)C)c(O)cc6O)n[nH]c5=O)cc4)CC3)CC1)c1nnc(C)n1-2.Cl
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