MRGPRX4 modulator-2

Modify Date: 2025-08-26 15:04:07

MRGPRX4 modulator-2 Structure
MRGPRX4 modulator-2 structure
Common Name MRGPRX4 modulator-2
CAS Number 2492595-24-9 Molecular Weight 348.68
Density N/A Boiling Point N/A
Molecular Formula C15H9ClF4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRGPRX4 modulator-2


MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].

 Names

Name MRGPRX4 modulator-2

 MRGPRX4 modulator-2 Biological Activity

Description MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].
Related Catalog
Target

IC50: < 100 nM (MRGPR X4)[1]

References

[1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)

 Chemical & Physical Properties

Molecular Formula C15H9ClF4O3
Molecular Weight 348.68
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