hCAI/II-IN-3
Modify Date: 2024-01-13 11:05:04
hCAI/II-IN-3 structure
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Common Name | hCAI/II-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2480283-93-8 | Molecular Weight | 394.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H18N4O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of hCAI/II-IN-3hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki values of 51.25, 13.15 and 42.18 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-3 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1]. |
| Name | hCAI/II-IN-3 |
|---|
| Description | hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki values of 51.25, 13.15 and 42.18 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-3 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1]. |
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| Related Catalog | |
| In Vitro | hCAI/II-IN-3 (compound 5b) (5-200 μM, 48 hours; HEK293T cells) has no obvious toxicity at HEK293T cells[1]. Cell Cytotoxicity Assay[1] Cell Line: Embryonic kidney (HEK293T) cells Concentration: 5, 25, 50, 100 and 200 μM Incubation Time: 48 hours Result: Had no apparent cytotoxicity. |
| References |
| Molecular Formula | C16H18N4O4S2 |
|---|---|
| Molecular Weight | 394.47 |