Surfactin
Surfactin structure
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Common Name | Surfactin | ||
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| CAS Number | 24730-31-2 | Molecular Weight | 1036.34000 | |
| Density | 1.037±0.06 g/cm3 | Boiling Point | 1268.3±65.0℃ | |
| Molecular Formula | C53H93N7O13 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of SurfactinSurfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects[1][2]. Surfactin also has antiviral activity against a variety of enveloped viruses[3]. |
| Name | surfactin C |
|---|---|
| Synonym | More Synonyms |
| Description | Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects[1][2]. Surfactin also has antiviral activity against a variety of enveloped viruses[3]. |
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| Related Catalog | |
| Target |
HSV-1 HSV-2 |
| In Vitro | Surfactin can increase the activity of Amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC). For APEC O78 strain, the MIC of Amoxicillin and Surfactin are 1000 ug/ml and >1mg/ml, respectively[1]. |
| In Vivo | In the model of chick infection (inoculation of E.coli), Surfactin exerts adjuvant effects with Amoxicillin against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al. Surfactin can act as a novel antimicrobial adjuvant with Amoxicillin against AEPC infection in chicken[1]. |
| References |
| Density | 1.037±0.06 g/cm3 |
|---|---|
| Boiling Point | 1268.3±65.0℃ |
| Molecular Formula | C53H93N7O13 |
| Molecular Weight | 1036.34000 |
| Exact Mass | 1035.68000 |
| PSA | 304.60000 |
| LogP | 7.34390 |
| InChIKey | NJGWOFRZMQRKHT-ISBLQWLTSA-N |
| SMILES | CC(C)CCCCCCCCCC1CC(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)O1 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Pectin Enhances Bio-Control Efficacy by Inducing Colonization and Secretion of Secondary Metabolites by Bacillus amyloliquefaciens SQY 162 in the Rhizosphere of Tobacco.
PLoS ONE 10 , e0127418, (2015) Bacillus amyloliquefaciens is a plant-beneficial Gram-positive bacterium involved in suppressing soil-borne pathogens through the secretion of secondary metabolites and high rhizosphere competence. Bi... |
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Effects of surfactin on membrane models displaying lipid phase separation.
Biochim. Biophys. Acta 1828(2) , 801-15, (2013) Surfactin, a bacterial amphiphilic lipopeptide is attracting more and more attention in view of its bioactive properties which are in relation with its ability to interact with lipids of biological me... |
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Direct surfactin-gramicidin S antagonism supports detoxification in mixed producer cultures of Bacillus subtilis and Aneurinibacillus migulanus.
Microbiology 158(Pt 12) , 3072-82, (2012) Antibiotic production as a defence mechanism is a characteristic of a wide variety of organisms. In natural evolutionary adaptation, cellular events such as sporulation, biofilm formation and resistan... |
| MFCD00082048 |