Insulin β Chain Peptide (15-23)

Modify Date: 2024-01-09 13:04:35

Insulin β Chain Peptide (15-23) Structure
Insulin β Chain Peptide (15-23) structure
Common Name Insulin β Chain Peptide (15-23)
CAS Number 247044-67-3 Molecular Weight 1009.18
Density N/A Boiling Point N/A
Molecular Formula C44H72N12O13S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Insulin β Chain Peptide (15-23)


Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. The Insulin β Chain Peptide (15-23) tetramer stained the INS-reactive CTL clone G9C8, but neither this tetramer nor the negative control tetramer (TUM) stained the splenic CD8+ T cells from NOD or 8.3-TCRαβtransgenic NOD mice[1][2].

 Names

Name Insulin β Chain Peptide (15-23)

 Insulin β Chain Peptide (15-23) Biological Activity

Description Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. The Insulin β Chain Peptide (15-23) tetramer stained the INS-reactive CTL clone G9C8, but neither this tetramer nor the negative control tetramer (TUM) stained the splenic CD8+ T cells from NOD or 8.3-TCRαβtransgenic NOD mice[1][2].
Related Catalog
References

[1]. Amrani A, et al. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature. 2000;406(6797):739-742.

[2]. Takaki T, et al. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. J Immunol. 2004;173(4):2530-2541.

 Chemical & Physical Properties

Molecular Formula C44H72N12O13S
Molecular Weight 1009.18