Thalidomide-5-O-CH2-COOH

Modify Date: 2024-04-06 22:31:37

Thalidomide-5-O-CH2-COOH Structure
Thalidomide-5-O-CH2-COOH structure
Common Name Thalidomide-5-O-CH2-COOH
CAS Number 2467425-53-0 Molecular Weight 332.26
Density N/A Boiling Point N/A
Molecular Formula C15H12N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-5-O-CH2-COOH


Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.

 Names

Name Acetic acid, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]oxy]-

 Thalidomide-5-O-CH2-COOH Biological Activity

Description Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C15H12N2O7
Molecular Weight 332.26
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