Bafisontamab

Modify Date: 2024-04-05 19:48:00

Bafisontamab Structure
Bafisontamab structure
Common Name Bafisontamab
CAS Number 2437210-79-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bafisontamab


Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].

 Names

Name Bafisontamab

 Bafisontamab Biological Activity

Description Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].
Related Catalog
Target

EGFR

c-Met

In Vivo Bafisontamab (EMB-01) 在 PDX 和 CDX 肿瘤模型中诱导的抗肿瘤活性明显强于抗 EGFR 单抗或抗 cMet 单抗。Bafisontamab 在抗 EGFR mAb 耐药肿瘤模型中表现出显著的抗肿瘤活性[1]。
References

[1]. Ren F, et al. EMB-01: An innovative bispecific antibody targeting EGFR and cMet on tumor cells mediates a novel mechanism to improve anti-tumor efficacy. Cancer Research, 2020, 80(16_Supplement): 528-528.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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