PROTAC RAF degrader 1
Modify Date: 2024-01-27 11:20:24
PROTAC RAF degrader 1 structure
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Common Name | PROTAC RAF degrader 1 | ||
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| CAS Number | 2413035-41-1 | Molecular Weight | 1010.18 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C51H57F2N9O7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC RAF degrader 1PROTAC RAF degrader 1 (compound 512) is a PROTAC RAF degrader. PROTAC RAF degrader 1 induces targeted degradation of BRAF mutants (DC50: 5.4 nM, 4.64 nM, 15.5 nM, 2.11 nM, 63.9 nM for BRAF V600E, V600K, G464V, G469A, K601E respectively). PROTAC RAF degrader 1 has anti-tumor activity. PROTAC RAF degrader 1 can be used for research of disorders that result from aggregation or accumulation of RAF, or the constitutive activation of RAF[1]. |
| Name | PROTAC RAF degrader 1 |
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| Description | PROTAC RAF degrader 1 (compound 512) is a PROTAC RAF degrader. PROTAC RAF degrader 1 induces targeted degradation of BRAF mutants (DC50: 5.4 nM, 4.64 nM, 15.5 nM, 2.11 nM, 63.9 nM for BRAF V600E, V600K, G464V, G469A, K601E respectively). PROTAC RAF degrader 1 has anti-tumor activity. PROTAC RAF degrader 1 can be used for research of disorders that result from aggregation or accumulation of RAF, or the constitutive activation of RAF[1]. |
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| References |
| Molecular Formula | C51H57F2N9O7S2 |
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| Molecular Weight | 1010.18 |