Lipoamido-PEG12-carboxylic Acid

Modify Date: 2024-01-09 20:24:26

Lipoamido-PEG12-carboxylic Acid Structure
Lipoamido-PEG12-carboxylic Acid structure
Common Name Lipoamido-PEG12-carboxylic Acid
CAS Number 2407442-47-9 Molecular Weight 806.03
Density N/A Boiling Point N/A
Molecular Formula C35H67NO15S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lipoamido-PEG12-carboxylic Acid


Lipoamido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Lipoamido-PEG12-acid

 Lipoamido-PEG12-carboxylic Acid Biological Activity

Description Lipoamido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C35H67NO15S2
Molecular Weight 806.03
Storage condition 2-8℃
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