Lotiglipron

Modify Date: 2025-08-25 10:37:49

Lotiglipron Structure
Lotiglipron structure
Common Name Lotiglipron
CAS Number 2401892-75-7 Molecular Weight 575.05
Density N/A Boiling Point N/A
Molecular Formula C31H31ClN4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lotiglipron


Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM)[1].

 Names

Name Lotiglipron

 Lotiglipron Biological Activity

Description Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM)[1].
Related Catalog
References

[1]. Buckeridge C, et al. Once-daily oral small molecule GLP-1R agonist PF-07081532 reduces glucose and body weight within 4-6 weeks in adults with type 2 diabetes and non-diabetic adults with obesity. Hybrid 58th EASD Annual Meeting; Sept 19–23, 2022 (abstr 114).

 Chemical & Physical Properties

Molecular Formula C31H31ClN4O5
Molecular Weight 575.05
InChIKey SVPYZAJTWFQTSM-UGDMGKLASA-N
SMILES CC1(c2ccc(Cl)cn2)Oc2cccc(C3CCN(Cc4nc5ccc(C(=O)O)cc5n4CC4CCO4)CC3)c2O1
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