Monomethyl auristatin E intermediate-16

Modify Date: 2025-08-25 12:06:49

Monomethyl auristatin E intermediate-16 Structure
Monomethyl auristatin E intermediate-16 structure
 Common Name Monomethyl auristatin E intermediate-16
CAS Number 2380991-16-0 Molecular Weight 363.45
Density N/A Boiling Point N/A
Molecular Formula C20H29NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Monomethyl auristatin E intermediate-16


Monomethyl auristatin E intermediate-16 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

 Names

Name Monomethyl auristatin E intermediate-16

 Monomethyl auristatin E intermediate-16 Biological Activity

Description Monomethyl auristatin E intermediate-16 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog
References

[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.  

 Chemical & Physical Properties

Molecular Formula C20H29NO5
Molecular Weight 363.45
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