CC-99282

Modify Date: 2025-08-26 00:44:39

CC-99282 Structure
CC-99282 structure
Common Name CC-99282
CAS Number 2379572-34-4 Molecular Weight 535.57
Density N/A Boiling Point N/A
Molecular Formula C28H30FN5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CC-99282


CC-99282 is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. CC-99282 can be used for researching non-Hodgkin lymphomas[1].

 Names

Name CC-99282

 CC-99282 Biological Activity

Description CC-99282 is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. CC-99282 can be used for researching non-Hodgkin lymphomas[1].
Related Catalog
Target

Cereblon

References

[1]. J.-M. Michot, et al. A PHASE 1, MULTICENTER, OPEN-LABEL STUDY OF CC-99282 ALONE AND IN COMBINATION WITH RITUXIMAB IN PATIENTS WITH RELAPSED OR REFRACTORY NON-HODGKIN LYMPHOMAS. Hematological Oncology. Volume 39, Issue S2, Jun. 2021.

 Chemical & Physical Properties

Molecular Formula C28H30FN5O5
Molecular Weight 535.57
InChIKey NZYDBVQXOGPDDU-QHCPKHFHSA-N
SMILES O=C1CCC(N2C(=O)c3cccc(NCc4ccc(CN5CC(N6CCOCC6)C5)cc4F)c3C2=O)C(=O)N1
Storage condition -20°C
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