MTP

Modify Date: 2025-08-25 13:59:30

MTP structure	Common Name	MTP
	CAS Number	2377372-62-6	Molecular Weight	516.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₃F₃N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MTP

MTP is a PKM2 inhibitor. MTP induces cancer cell apoptosis by modulating caspase-3 activation. MTP induces autophagy and increases ROS generation. MTP also inhibits JAK2 signaling. MTP can be used for research of oral squamous cell carcinoma[1].

Name	MTP

Description	MTP is a PKM2 inhibitor. MTP induces cancer cell apoptosis by modulating caspase-3 activation. MTP induces autophagy and increases ROS generation. MTP also inhibits JAK2 signaling. MTP can be used for research of oral squamous cell carcinoma[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Autophagy >> Autophagy
Target	JAK2
References	[1]. Weng JR, et al. A PKM2 inhibitor induces apoptosis and autophagy through JAK2 in human oral squamous cell carcinoma cells. Chem Biol Interact. 2023 Aug 1;380:110538.

Molecular Formula	C₂₉H₂₃F₃N₄O₂
Molecular Weight	516.51
InChIKey	UOGAVVINOTWELT-UHFFFAOYSA-N
SMILES	C#CC(=O)Nc1ccc(-n2nc(CCC(=O)NC)cc2-c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1

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MTP

Use of MTP

Names

MTP Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.