TCO-PEG6-NHS ester

Modify Date: 2025-08-27 12:10:06

TCO-PEG6-NHS ester Structure
TCO-PEG6-NHS ester structure
Common Name TCO-PEG6-NHS ester
CAS Number 2353409-96-6 Molecular Weight 602.67
Density N/A Boiling Point N/A
Molecular Formula C28H46N2O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCO-PEG6-NHS ester


TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name TCO-PEG6-NHS ester

 TCO-PEG6-NHS ester Biological Activity

Description TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

 Chemical & Physical Properties

Molecular Formula C28H46N2O12
Molecular Weight 602.67
InChIKey ADJYXGBSZXWRNW-UPHRSURJSA-N
SMILES O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)OC1CCC=CCCC1)ON1C(=O)CCC1=O
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