Ladanetin

Modify Date: 2024-01-16 20:14:59

Ladanetin Structure
Ladanetin structure
Common Name Ladanetin
CAS Number 23130-22-5 Molecular Weight 300.26300
Density 1.512g/cm3 Boiling Point 601.7ºC at 760mmHg
Molecular Formula C16H12O6 Melting Point N/A
MSDS N/A Flash Point 230.2ºC

 Use of Ladanetin


Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1].

 Names

Name 5,6-dihydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
Synonym More Synonyms

 Ladanetin Biological Activity

Description Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1].
Related Catalog
Target

IC50: 19.2 nM (Myeloperoxidase, MPO)[1].

In Vitro Sorbifolin (30 min) 显示出自由基清除活性,清除 ABTS 自由基和 DPPH 自由基的 IC50 分别为 5.7 μM 和 13.5 μM[1]。
References

[1]. Fernandes DC, et al. Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens. Chem Pharm Bull (Tokyo). 2008 May;56(5):723-6.  

 Chemical & Physical Properties

Density 1.512g/cm3
Boiling Point 601.7ºC at 760mmHg
Molecular Formula C16H12O6
Molecular Weight 300.26300
Flash Point 230.2ºC
Exact Mass 300.06300
PSA 100.13000
LogP 2.58540
Vapour Pressure 4.5E-15mmHg at 25°C
Index of Refraction 1.697

 Safety Information

HS Code 2914509090

 Synthetic Route

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Ladanetin Structure

Ladanetin

CAS#:23130-22-5

Literature: Krishnaswamy, N. R.; Rao, G. Nageswara; Omana, P. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 8 p. 750 - 752

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

7-O-methyl-seutellarin
5,6,4'-trihydroxy-7-methoxyflavone
7-methoxy-4',5,6-trihydroxyflavone
5,6-dihydroxy-7,4'-dimethoxyflavone
7-methylscutellarein
Sorbifolin
7-O-methyl-seutellarein
Ladanetin
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