STING modulator-5
Modify Date: 2024-04-03 02:45:35
STING modulator-5 structure
|
Common Name | STING modulator-5 | ||
|---|---|---|---|---|
| CAS Number | 2305940-22-9 | Molecular Weight | 871.88 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H45F4N11O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STING modulator-5STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1]. |
| Name | STING modulator-5 |
|---|
| Description | STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1]. |
|---|---|
| Related Catalog | |
| In Vitro | STING modulator-5 (4小时) 对外周血单核细胞 (PBMC) 有拮抗作用，pIC50 值为 8.1[1]。 STING modulator-5 对人 STING 的 C 端结构域 (CTD) 具有结合效力，通过 FRET 检测的 pIC50 值为 9.5[1]。 STING modulator-5 拮抗 THP-1 细胞的 pIC50 值为 8.9[1]。 |
| References |
[1]. Fosbenner, David T, et al. Modulators of stimulator of interferon genes. WO 2019/069270 Al. 2022. |
| Molecular Formula | C43H45F4N11O5 |
|---|---|
| Molecular Weight | 871.88 |