BRD7-IN-1 free base

Modify Date: 2025-09-11 15:40:33

BRD7-IN-1 free base structure	Common Name	BRD7-IN-1 free base
	CAS Number	2305379-66-0	Molecular Weight	394.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₆N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BRD7-IN-1 free base

BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1].

Name	BRD7-IN-1 free base

Description	BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD7, BRD9[1]
References	[1]. Zoppi V, et al. Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7. J Med Chem. 2019 Jan 24;62(2):699-726.

Molecular Formula	C₂₂H₂₆N₄O₃
Molecular Weight	394.47

Hazard Codes	Xi

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BRD7-IN-1 free base
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Purity: 98.0%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.