5,7,8-Trimethoxyflavone

Modify Date: 2025-08-26 18:25:13

5,7,8-Trimethoxyflavone structure	Common Name	5,7,8-Trimethoxyflavone
	CAS Number	23050-38-6	Molecular Weight	312.32
	Density	1.242±0.06 g/cm3 at 760 mmHg	Boiling Point	507.4±50.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₆O₅	Melting Point	167-168 °C
	MSDS	N/A	Flash Point	N/A

Use of 5,7,8-Trimethoxyflavone

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

Name	5,7,8-Trimethoxyflavone

Description	5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].
References	[1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.

Density	1.242±0.06 g/cm3 at 760 mmHg
Boiling Point	507.4±50.0 °C at 760 mmHg
Melting Point	167-168 °C
Molecular Formula	C₁₈H₁₆O₅
Molecular Weight	312.32
Storage condition	2-8°C

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5,7,8-Trimethoxyflavone

Use of 5,7,8-Trimethoxyflavone

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5,7,8-Trimethoxyflavone Biological Activity

Chemical & Physical Properties

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