PAD-IN-2
Modify Date: 2025-10-09 07:39:38
PAD-IN-2 structure
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Common Name | PAD-IN-2 | ||
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| CAS Number | 2304852-21-7 | Molecular Weight | 490.00 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28ClN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PAD-IN-2PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1]. |
| Name | PAD-IN-2 |
|---|
| Description | PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1]. |
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| Related Catalog | |
| In Vitro | PAD-IN-2 (Example-57, 1 h) inhibits PAD4 activity with an IC50 value <1 μM (determined by ammonia release biochemical assay)[1]. |
| References |
[1]. Hallur, Gurulingappa, et al. Heterocyclic compounds as pad4 inhibitors. Patent WO2019058393 A1. |
| Molecular Formula | C27H28ClN5O2 |
|---|---|
| Molecular Weight | 490.00 |
| InChIKey | VWMILHOMRPKNRL-LJQANCHMSA-N |
| SMILES | NC1CCCN(C(=O)c2cc3c4c(c2)nc(-c2cc5cccc(Cl)c5n2CC2CC2)n4CCO3)C1 |