2,4-Thiazolidinedione structure
|
Common Name | 2,4-Thiazolidinedione | ||
|---|---|---|---|---|
| CAS Number | 2295-31-0 | Molecular Weight | 117.13 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 178-179 ºC (19 mmHg) | |
| Molecular Formula | C3H3NO2S | Melting Point | 123-126 ºC | |
| MSDS | Chinese USA | Flash Point | 138.7±19.3 °C | |
Use of 2,4-Thiazolidinedione2,4-Thiazolidinedione is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Name | 1,3-thiazolidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
| Description | 2,4-Thiazolidinedione is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | |
| In Vitro | PPARγ 激动剂。胰岛素增敏剂。 |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 178-179 ºC (19 mmHg) |
| Melting Point | 123-126 ºC |
| Molecular Formula | C3H3NO2S |
| Molecular Weight | 117.13 |
| Flash Point | 138.7±19.3 °C |
| Exact Mass | 116.988449 |
| PSA | 71.47000 |
| LogP | -0.54 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.577 |
| InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N |
| SMILES | O=C1CSC(=O)N1 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | XJ5775000 |
| HS Code | 2942000000 |
| Precursor 6 | |
|---|---|
| DownStream 10 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Cytotoxicity of thiazolidinedione-, oxazolidinedione- and pyrrolidinedione-ring containing compounds in HepG2 cells.
Toxicol. In Vitro 29 , 1887-96, (2015) Liver damage occurred in some patients who took troglitazone (TGZ) for type II diabetes. The 2,4-thiazolidinedione (TZD) ring in TGZ's structure has been implicated in its hepatotoxicity. To further e... |
|
|
Differential cardiovascular outcomes after dipeptidyl peptidase-4 inhibitor, sulfonylurea, and pioglitazone therapy, all in combination with metformin, for type 2 diabetes: a population-based cohort study.
PLoS ONE 10 , e0124287, (2015) Data on the comparative effectiveness of oral antidiabetics on cardiovascular outcomes in a clinical practice setting are limited. This study sought to determine whether a differential risk of cardiov... |
|
|
Effects of Various 5,7-Dihydroxyflavone Analogs on Adipogenesis in 3T3-L1 Cells.
Biol. Pharm. Bull. 38 , 1794-800, (2015) We studied the effects of twelve 5,7-dihydroxyflavone analogs on adipogenesis in 3T3-L1 cells. Among the compounds, luteolin, diosmetin, and chrysoeriol partly inhibited adipogenesis by blocking the a... |
| EINECS 218-941-2 |
| 2(5H)-Thiazolone, 4-hydroxy- |
| 2,4-Thiazolidindione |
| usafek-5496 |
| 2,4-dioxothiazolidine |
| Thiazolidinedione |
| 2,4-Thiazolidinedione |
| 1,3-Thiazolidine-2,4-dione |
| 2-thiazolidin-4-one |
| 2,4-thiazolidinone |
| thiazolidine-2,4-dione |
| 2,4-Thiazolinedione |
| 4-Hydroxy-1,3-thiazol-2(5H)-one |
| MFCD00005478 |
| TZD |