N,N'-DME-N-PEG2-Boc

Modify Date: 2024-01-09 11:04:38

N,N'-DME-N-PEG2-Boc Structure
N,N'-DME-N-PEG2-Boc structure
Common Name N,N'-DME-N-PEG2-Boc
CAS Number 2279944-69-1 Molecular Weight 304.43
Density N/A Boiling Point N/A
Molecular Formula C15H32N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N,N'-DME-N-PEG2-Boc


N,N'-DME-N-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N,N'-DME-N-PEG2-Boc

 N,N'-DME-N-PEG2-Boc Biological Activity

Description N,N'-DME-N-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H32N2O4
Molecular Weight 304.43
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