XSJ2-46

Modify Date: 2025-08-28 19:14:33

XSJ2-46 Structure
XSJ2-46 structure
Common Name XSJ2-46
CAS Number 2265911-12-2 Molecular Weight 548.94
Density N/A Boiling Point N/A
Molecular Formula C25H24ClF3N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of XSJ2-46


XSJ2-46, 5'-amino NI analog, is an antiviral agent. XSJ2-46 has anti-Zika virus activity. XSJ2-46 exhibits reasonable inhibition of RNA-dependent RNA polymerases (RdRp) with an IC50 value of 8.78 μM[1].

 Names

Name XSJ2-46

 XSJ2-46 Biological Activity

Description XSJ2-46, 5'-amino NI analog, is an antiviral agent. XSJ2-46 has anti-Zika virus activity. XSJ2-46 exhibits reasonable inhibition of RNA-dependent RNA polymerases (RdRp) with an IC50 value of 8.78 μM[1].
Related Catalog
Target

IC50: 8.78 μM (RdRp)[1].

References

[1]. Chen X, et al. Investigation of novel 5'-amino adenosine derivatives with potential anti-Zika virus activity. Eur J Med Chem. 2023 Oct 1;261:115852.  

 Chemical & Physical Properties

Molecular Formula C25H24ClF3N6O3
Molecular Weight 548.94
InChIKey YXVLDZLVROXMQN-UMCMBGNQSA-N
SMILES OC1C(CNCc2ccc(C(F)(F)F)cc2)OC(n2cnc3c(NCc4cccc(Cl)c4)ncnc32)C1O
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