Bacitracin A1 (9CI)

Modify Date: 2024-01-08 12:26:02

Bacitracin A1 (9CI) Structure
Bacitracin A1 (9CI) structure
Common Name Bacitracin A1 (9CI)
CAS Number 22601-59-8 Molecular Weight 1422.69000
Density 1.43 g/cm3 Boiling Point 1755.5ºC at 760 mmHg
Molecular Formula C66H103N17O16S Melting Point N/A
MSDS USA Flash Point 1015.5ºC

 Names

Name bacitracin A
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.43 g/cm3
Boiling Point 1755.5ºC at 760 mmHg
Molecular Formula C66H103N17O16S
Molecular Weight 1422.69000
Flash Point 1015.5ºC
Exact Mass 1421.75000
PSA 556.17000
LogP 3.72410
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CP0350000
CHEMICAL NAME :
Bacitracin A
CAS REGISTRY NUMBER :
22601-59-8
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C66-H103-N17-O16-S
MOLECULAR WEIGHT :
1422.92
WISWESSER LINE NOTATION :
T5N CS AUTJ BYZY2 EVMY1Y&&VMY2VQVMYY2&&VM-WT-23-VM DVM GVM JVM MVM QVMTJ C3Z FY2 I1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
158 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity)
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
474 mg/kg/3D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,417,1951

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles26

More Articles
Validation of a quantitative HPLC method for bacitracin and bacitracin zinc using EDTA as a mobile-phase modifier.

J. Pharm. Biomed. Anal. 70 , 619-23, (2012)

Any product marketed in the United States and labeled bacitracin must comply with the tests, procedures, and acceptance criteria in the relevant monograph published in the US Pharmacopeia (USP). The t...

Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery.

Proc. Natl. Acad. Sci. U. S. A. 109(47) , 19196-201, (2012)

Nonribosomal peptides are highly sought after for their therapeutic applications. As with other natural products, dereplication of known compounds and focused discovery of new agents within this class...

Affinity capillary electrophoresis study of the linkage existing between proton and zinc ion binding to bacitracin A1.

Electrophoresis 24(5) , 801-7, (2003)

Measurements by capillary electrophoresis (CE) of bacitracin A(1) effective mobility at different pH values permitted to estimate the five acidic dissociation constants and the Stokes radii at differe...

 Synonyms

Verrucarin A,7'-deoxo-2'-deoxy-2',3'-epoxy-3-hydroxy-7'-(1-hydroxyethyl)-,(2'S,3S,3'R,7'R(R))
baccharinoid B12
(2'S,3S,3'R,7'R(R))-7'-Deoxo-2'-deoxy-2',3'-epoxy-3-hydroxy-7'-(1-hydroxyethyl)verrucarin A
Solu-Tracin 50
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