Py-MAA-Val-Cit-PAB-MMAE

Modify Date: 2024-01-29 07:16:04

Py-MAA-Val-Cit-PAB-MMAE structure	Common Name	Py-MAA-Val-Cit-PAB-MMAE
	CAS Number	2247398-68-9	Molecular Weight	1446.79
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₂H₁₁₁N₁₃O₁₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Py-MAA-Val-Cit-PAB-MMAE

Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) is an ADC Linker of Zapadcine-3a. Zapadcine-3a is an anti-TRAILR2 ADC with broad spectrum, and antineoplastic effect. Zapadcine-3a can be swallowed up into lysosome of tumor cells by binding to TRAILR2. Then Zapadcine-3a releases small molecular compound to specifically kill various TRAILR2-pos. Zapadcine-3a potently eradicates tumor cells and cures tumor[1].

Name	Py-MAA-Val-Cit-PAB-MMAE

Description	Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) is an ADC Linker of Zapadcine-3a. Zapadcine-3a is an anti-TRAILR2 ADC with broad spectrum, and antineoplastic effect. Zapadcine-3a can be swallowed up into lysosome of tumor cells by binding to TRAILR2. Then Zapadcine-3a releases small molecular compound to specifically kill various TRAILR2-pos. Zapadcine-3a potently eradicates tumor cells and cures tumor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	CD262
References	[1]. Zheng Dexia, et al. Anti-tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAILR2) antibody-drug conjugate (ADC) and its pharmaceutical application in antineoplastic therapy: China, CN108452320. 2018-08-28.

Molecular Formula	C₇₂H₁₁₁N₁₃O₁₆S
Molecular Weight	1446.79

Py-MAA-Val-Cit-PAB-MMAE

Use of Py-MAA-Val-Cit-PAB-MMAE

Names

Py-MAA-Val-Cit-PAB-MMAE Biological Activity

Chemical & Physical Properties