IACS-8779 disodium

Modify Date: 2024-01-10 00:12:40

IACS-8779 disodium Structure
IACS-8779 disodium structure
Common Name IACS-8779 disodium
CAS Number 2243079-27-6 Molecular Weight 733.52
Density N/A Boiling Point N/A
Molecular Formula C21H23N9Na2O10P2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IACS-8779 disodium


IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].

 Names

Name IACS-8779 disodium

 IACS-8779 disodium Biological Activity

Description IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].
Related Catalog
References

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

 Chemical & Physical Properties

Molecular Formula C21H23N9Na2O10P2S2
Molecular Weight 733.52