E7766 diammonium salt
Modify Date: 2025-08-25 09:10:47
E7766 diammonium salt structure
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Common Name | E7766 diammonium salt | ||
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| CAS Number | 2242635-03-4 | Molecular Weight | 780.66 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H32F2N12O8P2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of E7766 diammonium saltE7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities[1]. |
| Name | E7766 diammonium salt |
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| Description | E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities[1]. |
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| Related Catalog | |
| In Vitro | E7766 diammonium salt inhibits four human STING variants, human wild-type, HAQ, AQ and REF STING proteins, with EC50 values of 1 μM, 2.2 μM, 1.2 μM and 4.9 μM, respectively[1]. |
| In Vivo | In murine colon cancer model, a single intratumoral injection of 10 mg/kg E7766 diammonium salt in the subcutaneous tumor. E7766 diammonium salt is shown to have potent antitumor activity with long lasting immune memory response in a mouse liver metastatic tumor model[1]. |
| References |
| Molecular Formula | C24H32F2N12O8P2S2 |
|---|---|
| Molecular Weight | 780.66 |