TK4g

Modify Date: 2025-11-09 17:55:46

TK4g structure	Common Name	TK4g
	CAS Number	2232890-86-5	Molecular Weight	385.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₉N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TK4g

TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1].

Name	TK4g

Description	TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK2:12.61 nM (IC50) JAK3:15.80 nM (IC50)
References	[1]. Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

Molecular Formula	C₁₉H₁₉N₃O₄S
Molecular Weight	385.44
InChIKey	YUDCYGWINRMCBG-UHFFFAOYSA-N
SMILES	CCn1c(C)c(C(=O)c2ccccc2)c(=O)n1-c1cccc(S(N)(=O)=O)c1

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