BK50164
Modify Date: 2025-08-26 16:07:12
BK50164 structure
|
Common Name | BK50164 | ||
|---|---|---|---|---|
| CAS Number | 2204291-78-9 | Molecular Weight | 405.72 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13ClFN5O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BK50164BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM. BK50164 binds to CD99 with a KD value of 1.5 µM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1]. |
| Name | BK50164 |
|---|
| Description | BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM. BK50164 binds to CD99 with a KD value of 1.5 µM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 13.089 µM (CD73)[1] |
| In Vitro | BK50164 (0-400 µM；48 小时) 显示抗增殖活性，对 A4573, TC-32, TC-71, Saos-2, U-2 OS 细胞的 IC50 值分别为35.8, 34.28, 5.17, ≥400, ≥400 µM[2]。 BK50164 (4-16 µM; 48 h) 诱导细胞凋亡和细胞周期停滞在 Sub-G1 期[2]。 Cell Viability Assay[2] Cell Line: A4573, TC-32, TC-71, Saos-2, U-2 OS cells Concentration: 0-400 µM Incubation Time: 48 h Result: Inhibited cell viability witn IC50s of 35.8, 34.28, 5.17, ≥400, ≥400 µM for A4573, TC-32, TC-71, Saos-2, U-2 OS cells, respectively. Cell Cycle Analysis[2] Cell Line: TC-32, U-2 OS cells Concentration: 4, 8, 16 µM Incubation Time: 48 h Result: Induced apoptosis in only TC-32 ES cells but not in U-2 OS cell line and induces cell cycle arrest at Sub-G1 phase. |
| References |
| Molecular Formula | C13H13ClFN5O7 |
|---|---|
| Molecular Weight | 405.72 |