OAT1/3-IN-2

Modify Date: 2025-08-25 18:41:05

OAT1/3-IN-2 Structure
OAT1/3-IN-2 structure
Common Name OAT1/3-IN-2
CAS Number 2195434-05-8 Molecular Weight 328.32
Density N/A Boiling Point N/A
Molecular Formula C18H16O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of OAT1/3-IN-2


OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage[1].

 Names

Name OAT1/3-IN-2

 OAT1/3-IN-2 Biological Activity

Description OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage[1].
Related Catalog
Target

Organic anion transporter 1 and 3 (OAT1 and OAT3)[1]

References

[1]. Wang X, et al. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. Toxicol Sci. 2018 Feb 1;161(2):321-334.  

 Chemical & Physical Properties

Molecular Formula C18H16O6
Molecular Weight 328.32
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