Bostrycin

Modify Date: 2025-08-24 21:13:30

Bostrycin Structure
Bostrycin structure
Common Name Bostrycin
CAS Number 21879-81-2 Molecular Weight 336.29300
Density N/A Boiling Point N/A
Molecular Formula C16H16O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bostrycin


Bostrycin is an anthraquinone with antibacterial, antiproliferative, and phytotoxic properties. It is active against Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum. Bostrycin inhibits proliferation of A549 lung adenocarcinoma cells as well as halts the cell cycle at the G0/G1 phase and induces apoptosis in A549 cells. Bostrycin has been used as a cross-linking agent for protein immobilization that retains bacteriostatic activity when immobilized on nonwoven polypropylene fabric.

 Names

Name deoxybostrycin
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C16H16O8
Molecular Weight 336.29300
Exact Mass 336.08500
PSA 144.52000
InChIKey ZQNOLGRKZRDRQO-XHSDSOJGSA-N
SMILES COC1=CC(=O)c2c(O)c3c(c(O)c2C1=O)CC(C)(O)C(O)C3O

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB8068000
CHEMICAL NAME :
Anthraquinone, 1,2,3,4-tetrahydro-1-beta,2-beta,3-beta,5,8-pentahydr oxy-6-methoxy-3-methy l-
CAS REGISTRY NUMBER :
21879-81-2
LAST UPDATED :
198211
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H16-O8
MOLECULAR WEIGHT :
336.32
WISWESSER LINE NOTATION :
L C666 BV IV&&TJ DQ EO1 GQ KQ LQ MQ M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 3,231,1980

 Synonyms

(+)-bostrycin
(5R,6R,7S)-5,6,7,9,10-pentahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione
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