TLR7/8/9-IN-1

Modify Date: 2024-01-11 05:18:40

Use of TLR7/8/9-IN-1

TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9).

Name	BMS-615

Description	TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9).
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
References	[1]. Mussari CP, et al. Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). ACS Med Chem Lett. 2020 Jul 29;11(9):1751-1758.

Molecular Formula	C₂₇H₃₇N₃O₂
Molecular Weight	435.61
Storage condition	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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