cis-1-fluoro-4-OTBS-cyclohexane
Modify Date: 2024-08-29 19:22:42
cis-1-fluoro-4-OTBS-cyclohexane structure
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Common Name | cis-1-fluoro-4-OTBS-cyclohexane | ||
|---|---|---|---|---|
| CAS Number | 2173014-90-7 | Molecular Weight | 232.41 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 234.0±33.0 °C at 760 mmHg | |
| Molecular Formula | C12H25FOSi | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 95.3±25.4 °C | |
Use of cis-1-fluoro-4-OTBS-cyclohexaneDescription The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexanol allows for the straightforward application in organic synthesis, after simple deprotection. It can be utilized to prepare fluorinated analogues of known compounds. |
| Name | cis-1-fluoro-4-OTBS-cyclohexane |
|---|---|
| Synonym | More Synonyms |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 234.0±33.0 °C at 760 mmHg |
| Molecular Formula | C12H25FOSi |
| Molecular Weight | 232.41 |
| Flash Point | 95.3±25.4 °C |
| Exact Mass | 232.165863 |
| LogP | 4.32 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.428 |
| Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis- |
| [(cis-4-Fluorocyclohexyl)oxy](dimethyl)(2-methyl-2-propanyl)silane |