RK-582

Modify Date: 2024-02-01 17:07:17

RK-582 Structure
RK-582 structure
Common Name RK-582
CAS Number 2171388-28-4 Molecular Weight 510.6144
Density N/A Boiling Point N/A
Molecular Formula C27H35FN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RK-582


RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

 Names

Name RK-582

 RK-582 Biological Activity

Description RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

 Chemical & Physical Properties

Molecular Formula C27H35FN6O3
Molecular Weight 510.6144
InChIKey KZUPFZKALLNBBV-CALCHBBNSA-N
SMILES CC1CN(c2cc(F)c3c(c2)N(C)C(=O)C32CCN(c3nc4c(c(=O)[nH]3)CCCN4C)CC2)CC(C)O1
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