mPEG16-Propyne

Modify Date: 2024-01-08 14:34:01

mPEG16-Propyne Structure
mPEG16-Propyne structure
Common Name mPEG16-Propyne
CAS Number 2169967-47-7 Molecular Weight 774.93
Density N/A Boiling Point N/A
Molecular Formula C36H70O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mPEG16-Propyne


Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG17-methane

 mPEG16-Propyne Biological Activity

Description Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C36H70O17
Molecular Weight 774.93