WY-135

Modify Date: 2025-08-27 18:59:14

WY-135 structure	Common Name	WY-135
	CAS Number	2163060-83-9	Molecular Weight	612.15
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₄ClN₉O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of WY-135

WY-135 is a ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.

Name	WY-135

Description	WY-135 is a ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: 1.4 nM (ALK), 1.1 nM (ROS1)[1]
References	[1]. Wang Y, et al. Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R. Eur J Med Chem. 2018 Jan 1;143:123-136.

Molecular Formula	C₂₈H₃₄ClN₉O₃S
Molecular Weight	612.15

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-chloro-2-N-[2-methoxy-4-[4-[(4-methylpiperazin-1-yl)methyl]triazol-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: WY-135
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: WY-135
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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