PROTAC ER Degrader-3
Modify Date: 2025-08-25 15:40:06
PROTAC ER Degrader-3 structure
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Common Name | PROTAC ER Degrader-3 | ||
|---|---|---|---|---|
| CAS Number | 2158322-29-1 | Molecular Weight | 1220.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C71H77N7O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC ER Degrader-3PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab). |
| Name | PROTAC ER Degrader-3 |
|---|
| Description | PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab). |
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| Related Catalog | |
| References |
[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1. |
| Molecular Formula | C71H77N7O12 |
|---|---|
| Molecular Weight | 1220.41 |
| InChIKey | ZBSUUCSLUPVKFV-OFHFNDNJSA-N |
| SMILES | CCC(=C(c1ccc(O)cc1)c1ccc(OCCN(C)C(=O)COCCOCCNC(=O)c2ccc(C(=O)N3c4cc(C#N)ccc4N(Cc4c(OC)ccc5ccccc45)C(=O)C(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)C3C)cc2)cc1)c1ccccc1 |
| Storage condition | 2-8℃ |