Bruceine D
Modify Date: 2024-01-02 12:33:22
Bruceine D structure
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Common Name | Bruceine D | ||
|---|---|---|---|---|
| CAS Number | 21499-66-1 | Molecular Weight | 410.415 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 661.3±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H26O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 235.8±25.0 °C | |
Use of Bruceine DBruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity[1][2]. |
| Name | bruceine D |
|---|---|
| Synonym | More Synonyms |
| Description | Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Notch[1] |
| In Vitro | Bruceine D inhibits the cell viability of H460 and A549 cells in a dose-dependent manner with IC50 values of 0.5 and 0.6 μM, respectively, at 48 h of treatment[1]. Bruceine D (0.125-1.0 μM) dose-dependently promotes chromatin condensation, Annexin V-positive cell population and caspase-dependent apoptosis in H460 and A549 cells[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 661.3±55.0 °C at 760 mmHg |
| Molecular Formula | C20H26O9 |
| Molecular Weight | 410.415 |
| Flash Point | 235.8±25.0 °C |
| Exact Mass | 410.157684 |
| PSA | 153.75000 |
| LogP | -0.50 |
| Vapour Pressure | 0.0±4.5 mmHg at 25°C |
| Index of Refraction | 1.670 |
| Storage condition | 2-8C |
| BRUCEIND |
| Bruceine D |
| (1β,9ξ,11β,12α,15β)-1,11,12,14,15-Pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione |
| Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,9ξ,11β,12α,15β)- |
- BioBioPha
- China
- Product Name: Bruceine D
- Price: ￥Inquiry/10mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Bruceine D
- Price: ￥960.0/5mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
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Price: ￥1008/5mg
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