PF-06700841 P-Tosylate

Modify Date: 2024-01-16 20:31:33

PF-06700841 P-Tosylate structure	Common Name	PF-06700841 P-Tosylate
	CAS Number	2140301-96-6	Molecular Weight	561.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₉F₂N₇O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF-06700841 P-Tosylate

PF-06700841 P-Tosylate is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].

Name	PF-06700841 P-Tosylate

Description	PF-06700841 P-Tosylate is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	IC50: 17 nM (JAK1), 23 nM (TYK2)[1]
References	[1]. Fensome A, et al. Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841). J Med Chem. 2018 Oct 11;61(19):8597-8612.

Molecular Formula	C₂₅H₂₉F₂N₇O₄S
Molecular Weight	561.60
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: PF-06700841 free base
Price: $850.0/100mg $1500.0/250mg $3200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥990/5 mg

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