HS79

Modify Date: 2024-01-06 13:17:51

HS79 Structure
HS79 structure
Common Name HS79
CAS Number 2138838-56-7 Molecular Weight 338.47
Density N/A Boiling Point N/A
Molecular Formula C19H22N4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS79


HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

 Names

Name HS79

 HS79 Biological Activity

Description HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.
Related Catalog
Target

FASN[1]

In Vitro Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].
References

[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

 Chemical & Physical Properties

Molecular Formula C19H22N4S
Molecular Weight 338.47
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