Syn-TEF1
Modify Date: 2024-01-05 13:21:20
Syn-TEF1 structure
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Common Name | Syn-TEF1 | ||
|---|---|---|---|---|
| CAS Number | 2135880-19-0 | Molecular Weight | 1675.334 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C77H104ClN23O16S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Syn-TEF1Syn-TEF1 is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia, license transcription elongation at targeted genomic loci; targets the DNA sequence 5'-AAGAAGAAG-3', activate FXN expression in primary patient cells and patient-derived fibroblasts, iPSCs, cardiomyocytes, sensory neurons, and mouse xenografts. |
| Name | Syn-TEF1 |
|---|
| Description | Syn-TEF1 is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia, license transcription elongation at targeted genomic loci; targets the DNA sequence 5'-AAGAAGAAG-3', activate FXN expression in primary patient cells and patient-derived fibroblasts, iPSCs, cardiomyocytes, sensory neurons, and mouse xenografts. |
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| References | References 1. Erwin GS, et al. Science. 2017 Dec 22;358(6370):1617-1622. View Related Products by Target Other Targets |
| Molecular Formula | C77H104ClN23O16S |
|---|---|
| Molecular Weight | 1675.334 |